IRODAC-CT

IRODAC-CT is a prescription medication combining two potent antihypertensive agents: Irbesartan (150 mg) and Chlorthalidone (12.5 mg). This synergistic formulation is designed to effectively manage high blood pressure and reduce the risk of cardiovascular events, particularly in patients with comorbid conditions such as type 2 diabetes.

Composition:

• Irbesartan (150 mg): An angiotensin II receptor blocker (ARB) that relaxes blood vessels by inhibiting the action of angiotensin II, a hormone that causes vasoconstriction.

• Chlorthalidone (12.5 mg): A thiazide-like diuretic that helps eliminate excess sodium and water from the body, reducing blood volume and pressure.

Therapeutic Indications:

IRODAC-CT is indicated for:

• Hypertension (High Blood Pressure): Effective in lowering elevated blood pressure levels, thereby reducing the risk of stroke and heart attack.

• Cardiovascular Risk Reduction: Beneficial in patients with type 2 diabetes and hypertension, aiding in the prevention of cardiovascular complications.

Mechanism of Action:

The combination of Irbesartan and Chlorthalidone offers a dual mechanism to control blood pressure:

• Irbesartan: Blocks the binding of angiotensin II to its receptors, preventing vasoconstriction and promoting vasodilation.

• Chlorthalidone: Inhibits sodium reabsorption in the distal tubules of the kidneys, leading to increased excretion of sodium