MEROSEARCH-TZ

MEROSEARCH-TZ is a prescription medication formulated to treat a wide range of bacterial and parasitic infections. Combining two potent antimicrobial agents, Ciprofloxacin and Tinidazole, MEROSEARCH-TZ offers a broad-spectrum approach to combat infections caused by susceptible organisms.

Composition:

• Ciprofloxacin (500 mg): A fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, preventing DNA replication and leading to bacterial cell death.

• Tinidazole (600 mg): An antiprotozoal and antibacterial agent that disrupts DNA synthesis in anaerobic bacteria and protozoa, effectively eliminating the pathogens.

Therapeutic Indications:

MEROSEARCH-TZ is indicated for the treatment of various infections, including:

• Gastrointestinal Infections: Such as amoebiasis, giardiasis, and bacterial dysentery.

• Gynecological Infections: Including pelvic inflammatory disease and bacterial vaginosis.

• Respiratory Tract Infections: Such as bronchitis and pneumonia, caused by susceptible organisms.

• Urinary Tract Infections: Including cystitis and pyelonephritis.

Mechanism of Action:

The combination of Ciprofloxacin and Tinidazole provides a dual mechanism to combat infections:

• Ciprofloxacin: Inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination.

• Tinidazole: Enters the cells of anaerobic organisms and protozoa, where it is reduced to reactive intermediates that bind to DNA, causing strand breakage and cell